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In a Phase 2 trial that was published in the The New England Journal of Medicine participants achieved up to 24.2% average body weight loss at 48 week s while some higher dose groups gained 17.5% weight loss within just 24 weeks

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RTA + mFSP1 Egg phosphatidylcholine liposomes (1.03 mM) (prepared as previously described 46 ), STY-BODIPY (1.03 M), inhibitor (4.14 M), mFSP1 (16.55 nM) and FAD (331 nM) in pH 7.4 TBS buffer were added to the wells of a Nunc black polypropylene round-bottomed 96-well microplate (290 l)